Original article "Aluminum Vaccine Adjuvants: Are They Safe?" Translated from English MD. Ludmila Elek, language edited and translated the table Ing. Marián Fillo. christ stopped at eboli
Aluminum (Al) is scientifically proven neurotoxin and also the most commonly used adjuvant in vaccines. Despite nearly eighty years of widespread use of aluminum adjuvant medical science remarkably little understood their mechanism of action. In addition, there is a disturbing lack of data on toxicology and pharmacokinetics of these compounds. Nevertheless, it is usually filled by the idea that Al in vaccines is safe. However, experimental research christ stopped at eboli clearly shows that aluminum adjuvants have a potential christ stopped at eboli to cause serious human immunologic disorders. Aluminium in the form of an adjuvant in vaccines entails the risk of autoimmunity, prolonged inflammation of the brain and associated neurologic complications, and may have a deep and extensive consequences for health. In our opinion, christ stopped at eboli the medical and scientific community has not been rigorously considered the possibility that the benefits of vaccination may be overstated and the risk of possible side effects underestimated. We hope that this article will provide a framework for a much needed, but the outstanding research christ stopped at eboli on this highly controversial medical christ stopped at eboli topic.
aluminum adjuvant, adjuvant safety, autoimmunity, autism syndrome, Gulf War, multiple sclerosis, macrophage myofasciitida, neurotoxicity, seizures, Th2 immune response of the vaccine.
Aluminum is the most commonly used adjuvant christ stopped at eboli in vaccines and until recently were the only adjuvant licensed in the USA. [1-4] In his absence, the antigenic component of most vaccines (with the exception of live attenuated vaccines) are not able to induce an adequate immune response. [1], [5, 6] Paradoxically, despite nearly 90 years of use of aluminum adjuvants [3], their precise mechanism of action is understood very little. [1, 2] In addition, the increasing number of studies have shown a link with the use of these adducts of severe christ stopped at eboli autoimmune disorders in humans. [5-8] That there are concerns about the safety of Al adjuvants really justified, is evident from the general conclusion of the workshop Aluminum in Vaccines, held in Puerto christ stopped at eboli Rico in 2000. [2] The participants agreed in writing that the current lack of knowledge regarding the potential toxicity of adjuvant Al can be termed "prevailing uncertainty". Specific concerns were: "1) The toxicology and pharmacokinetics, particularly in infants and children, 2) the mechanisms by which Al adjuvant interacts christ stopped at eboli with the immune system, and 3) the need for adjuvant in booster (booster) doses." In the final paragraphs still report claims that "it has been demonstrated that the use of Al salts as an adjuvant is safe and effective." [2] In the light of the words "prevailing uncertainty", this statement seems very doubtful. With regard to the fact that the combined vaccine christ stopped at eboli with Al adjuvant applied often very young children (aged 2-6 months), often several at a time in one visit to a physician, [9, 10] may be concerns about the impact of the total body burden of aluminum vaccines really important. [11, 12] These areas deserve serious attention, because the best of our knowledge have been no adequate studies to evaluate the safety of simultaneous administration of several vaccines for young children. Another area of concern is the lack of any toxicological evaluation aluminum coadministration with other known toxins which are common constituents of vaccines, e.g. formaldehyde, mercury, phenoxyethanol, phenol, sodium borate, polysorbate 80, glutaraldehyde. [13, 14] Despite Al adjuvants are generally considered safe [2], [13] and some researchers have even recommended them to have to research in this area not spent any effort, although there is a "lack of good quality evidence." [15]
In the following, we give an overview of what is currently known about the Al adjuvant, their mechanisms of action and potential toxicity. First we present solid evidence to show that the effect of Al on various neurological disorders. Next, we discuss the current controversy christ stopped at eboli about the safety of Al adjuvants. Table 1: Toxicity of aluminum compounds for neurological development of various kinds of aluminum source / Compound Dose / route of administration duration species Adverse effects on neural development conventional solution for nutrition of infants ~ 20 mg / kg / day,> 10 days to live = intravenously (parenterally) aborted human infants Delayed developmental milestones in achieving korigovanom 18 months of age, as evidenced by the significantly lower Bayley Mental Development accomplished Index (BMDI = Bayley index of mental development). An average child loses 1 point BMDI for each day full of intravenous nutrition (after taking account of the optional disturbing factors) compared to children fed solutions without aluminum. [32] Al-containing antacids prolonged oral (mouth) minor children of craniosynostosis (premature ossification of skull au
No comments:
Post a Comment