Original article "Do aluminum dundrum on ice vaccine adjuvants Contribute to the rising prevalence of autism? "MD Translated from English. Ludmila Elek and linguistically edited by Ing. Marián Fillo.
Neural Dynamics Research Group (Group for Research on neural dynamics) Department of Ophthalmology and Visual Sciences (Department of ophthalmology and visual dundrum on ice sciences) University of British Columbia (University dundrum on ice of British Columbia), dundrum on ice 828 W. 10th Ave Vancouver, BC, V5Z 1L8 Canada (Canada) tel. : +1 604 875 4111 68 375 fax: +1 604 875 4376th e-mail: lucijat77@gmail.com
Department of Ophthalmology and Visual Sciences (Department of ophthalmology and visual sciences) Department of Experimental Medicine (Department of Experimental Medicine) Graduate Program in Neuroscience (Doctoral program in neurovied) University of British Columbia (University of British Columbia), 828 W. 10th Ave Vancouver, BC , V5Z 1L8 Canada (Canada)
Autism Spectrum Disorders (Autism Spectrum Disorders = ASD) are severe multisystem developmental disorders and urgent global public health problem. The basic defects in the ASD are dysfunctional immunity and impaired brain functions. Aluminum (Al), the most common adjuvants in vaccines is a proven neurotoxin and a strong dundrum on ice immune stimulant. For these reasons, the Al potential to cause disorders of the nervous and immune systems. When assessing the toxicity of adjuvants in children should be taken into account dundrum on ice two key points: the children can not be considered as "small adults" because of their unique physiology makes them more vulnerable dundrum on ice to the toxic effects; if the exposure is several vaccines with Al in adults can lead to cognitive impairment and autoimmunity, is it not reasonable to doubt the safety of current immunization schedules for children, which often contain 18 vaccines with adjuvants Al?
Using applications Hill criteria for determining causality between exposure and effect, we investigated whether exposure to Al from vaccines may contribute to an increase in ASD prevalence in Western countries. Our results show that it seems that children from countries with the highest incidence of ASD have the highest exposure to Al from vaccines; Al adjuvants increase exposure significantly dundrum on ice correlated with the observed increase in the prevalence of ASD in the US during the last twenty years (Pearson r = 0.92; p <0.0001); dundrum on ice There is a statistically significant correlation between the amount of Al applied to children starting school and the current prevalence of ASD in seven Western countries, especially after exposure age of 3-4 months (Pearson r = .89-.94, p = 0,0018- 0.0248).
Applications Hill criteria for this data shows that the correlation between the Al in vaccines and ASD may be causal. dundrum on ice Because children are part of the population that has the highest risk of complications after exposure to Al, it seems that it is necessary to more stringent safety evaluation Al adjuvant.
The brain during prenatal and early postnatal development extremely sensitive to the neurotoxic effects. [1] [2] Not only that this is generally a very sensitive period of rapid brain development, [3] but the blood-brain barrier (BBB) in this period is still incomplete and therefore much more permeable to the toxic substance. [2] [4] [5] In addition, stimulation of the immune system in the early stages of development (including vaccination) can lead to permanent damage to the functions of the nervous and immune systems. [6] [7] [8] [9] Experimental evidence also suggests that co-administration of only two to three immune adjuvants or repeated stimulation of the immune system with the same antigen in animals can overcome innate resistance to autoimmunity. [10] [11] Furthermore, many pathologies included in the "autoimmune / inflammatory syndrome induced adjuvants" ("Autoimmune / inflammatory syndrome induced by adjuvant" = "ASIA") are placed dundrum on ice in connection with the exposure of the Al adjuvant dundrum on ice in the vaccine (Table 1 ).
In many western countries reach children before they reach the age of 4-6 years, with a total of 23-32 routine vaccination vaccines. [12] [13] Many of them contain Al adjuvant. [2] [14] According to the US FDA (US Food and Drug Administration - The Food and Drug Administration in the USA) to evaluate dundrum on ice the safety of vaccines often do not include adequate toxicity tests because vaccines are not considered toxic in nature. [15] If, however, a few vaccines, applied to adults, may lead to adverse effects such as ASIA syndrome, we assume no experimental evidence that the current vaccination schedules are safe for children?
Analysis of relevant data shows that the number of vaccines recommended for children before entering school rose from 10 to late 70s to 32 in 2010 (18 of them containing Al adjuvant). [16] During the same period in the USA, the incidence of ASD by 2000%. [16] While these observations aroused interest in the potential role in the development of ASD vaccination remains controversial. ASD is characterized by a strong disrupted
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