NIMESIL - acute pain. | Package insert
Nimesil not be used: if you have hypersensitivity to nimesulide or to any of the excipients; If you specify a history of hypersensitivity reactions (eg., Bronchospasm, rhinitis, urticaria) on acetylsalicylic acid or other NSAIDs; if the former states of nimesulide hepatotoxicity; If gastric or duodenal active ulcer, history in order of recurrence of ulcers or bleeding from the gastrointestinal tract, blood spill in the brain and in other places, diseases caused by bleeding; If you have severe coagulation disorders; if you have severe heart disease; if you have severe renal impairment; If you have a liver dysfunction; If children younger than 12 years; If you are breast-feeding or third trimester. gmarket korea
Nimesil risk of side effects may be reduced if it is used for the minimum time possible. If the state of drug use, lack of improvement, should be discontinued. Nimesil treatment need to be completed, if there is an indication that may be symptoms gmarket korea of liver function (eg., Disturbed appetite, nausea, vomiting, abdominal pain, fatigue, dark urine) or altered liver function. These patients can not re-use of nimesulide. There are reports of liver damage, usually reversible when the drug was administered briefly. Along with Nimesil not use drugs that have known liver function, alcohol, which can increase the risk of liver damage. Nimesil administration, the patient does not have to take other pain-relieving drugs. We urge you to take along different non-steroidal anti-inflammatory agents. gmarket korea Gastrointestinal bleeding may occur, or ulcers and their perforation can occur at any period of treatment, the hazardous characteristics gmarket korea or not, as well as the absence of evidence gmarket korea of the existence of previous gastrointestinal symptoms. If there is bleeding from the gastrointestinal tract, or ulcers, nimesulide should be discontinued. Patients with a history of gastrointestinal problems, including a history of alleged peptic ulcer, bleeding from the gastrointestinal tract, ulcerative colitis or Crohn's disease, nimesulide should be used with caution. Patients with impaired renal or cardiac gmarket korea function, the medicine gmarket korea should be used in a prudent, because Nimesil gmarket korea consumption can lead to kidney problems. If renal function deteriorates, should be discontinued. Elderly patients are more common adverse non-steroidal anti-inflammatory effects, including bleeding from the gastrointestinal tract, intestinal perforation, kidney, heart and liver dysfunction. Therefore administration to maintain good control of the health condition. Nimesulide can interfere with platelet function, so patients predisposed to bleeding, it must be used with caution. Nimesil not a substitute for acetylsalicylic acid for cardiovascular prophylaxis. Non-steroidal anti-inflammatory drugs may mask fever resulting from bacterial diseases.
Nimesil gmarket korea can reduce a woman's fertility, so it is not recommended in women attempting to conceive. For women who find it difficult to get pregnant, also under investigation for infertility should stop taking this medicine.
Nimesil if used in combination with blood thinners can increase the effects of these drugs. If this combination can not refuse to be very careful monitoring of blood coagulation. Nimesulide can reduce some of the medicines gmarket korea that increase urine output, effect (furosemide). Co-administration of lithium and non-steroidal anti-inflammatory drugs may increase the plasma concentrations of lithium and increase the intensity of its side effects. If at one time used Nimesil and lithium, requires frequent monitoring of lithium levels in blood plasma. Nimesulide may increase the strength of the side effects of methotrexate, so it can be used 24 hours. or after 24 hours. after methotrexate administration. Nimesulide may increase the effects of cyclosporin kidneys.
Patients with impaired renal function, renal function impairment Some minor or moderate (creatinine clearance 30-80 ml / min.), A dose reduction is required. When severe renal impairment (creatinine clearance <30 ml / min). Nimesil prohibited.
Acute non-steroidal anti-inflammatory drugs overdose usually resulting symptoms include lethargy, drowsiness, nausea, vomiting, pain in the epigastric region, which, using supportive measures disappears. May include bleeding from the gastrointestinal tract. Although rare, but it can increase blood pressure, acute renal failure, respiratory depression, coma. The use of nonsteroidal anti-inflammatory therapeutic doses may be anaphylaxis-like reactions; they can be and medicine overdose
Nimesil not be used: if you have hypersensitivity to nimesulide or to any of the excipients; If you specify a history of hypersensitivity reactions (eg., Bronchospasm, rhinitis, urticaria) on acetylsalicylic acid or other NSAIDs; if the former states of nimesulide hepatotoxicity; If gastric or duodenal active ulcer, history in order of recurrence of ulcers or bleeding from the gastrointestinal tract, blood spill in the brain and in other places, diseases caused by bleeding; If you have severe coagulation disorders; if you have severe heart disease; if you have severe renal impairment; If you have a liver dysfunction; If children younger than 12 years; If you are breast-feeding or third trimester. gmarket korea
Nimesil risk of side effects may be reduced if it is used for the minimum time possible. If the state of drug use, lack of improvement, should be discontinued. Nimesil treatment need to be completed, if there is an indication that may be symptoms gmarket korea of liver function (eg., Disturbed appetite, nausea, vomiting, abdominal pain, fatigue, dark urine) or altered liver function. These patients can not re-use of nimesulide. There are reports of liver damage, usually reversible when the drug was administered briefly. Along with Nimesil not use drugs that have known liver function, alcohol, which can increase the risk of liver damage. Nimesil administration, the patient does not have to take other pain-relieving drugs. We urge you to take along different non-steroidal anti-inflammatory agents. gmarket korea Gastrointestinal bleeding may occur, or ulcers and their perforation can occur at any period of treatment, the hazardous characteristics gmarket korea or not, as well as the absence of evidence gmarket korea of the existence of previous gastrointestinal symptoms. If there is bleeding from the gastrointestinal tract, or ulcers, nimesulide should be discontinued. Patients with a history of gastrointestinal problems, including a history of alleged peptic ulcer, bleeding from the gastrointestinal tract, ulcerative colitis or Crohn's disease, nimesulide should be used with caution. Patients with impaired renal or cardiac gmarket korea function, the medicine gmarket korea should be used in a prudent, because Nimesil gmarket korea consumption can lead to kidney problems. If renal function deteriorates, should be discontinued. Elderly patients are more common adverse non-steroidal anti-inflammatory effects, including bleeding from the gastrointestinal tract, intestinal perforation, kidney, heart and liver dysfunction. Therefore administration to maintain good control of the health condition. Nimesulide can interfere with platelet function, so patients predisposed to bleeding, it must be used with caution. Nimesil not a substitute for acetylsalicylic acid for cardiovascular prophylaxis. Non-steroidal anti-inflammatory drugs may mask fever resulting from bacterial diseases.
Nimesil gmarket korea can reduce a woman's fertility, so it is not recommended in women attempting to conceive. For women who find it difficult to get pregnant, also under investigation for infertility should stop taking this medicine.
Nimesil if used in combination with blood thinners can increase the effects of these drugs. If this combination can not refuse to be very careful monitoring of blood coagulation. Nimesulide can reduce some of the medicines gmarket korea that increase urine output, effect (furosemide). Co-administration of lithium and non-steroidal anti-inflammatory drugs may increase the plasma concentrations of lithium and increase the intensity of its side effects. If at one time used Nimesil and lithium, requires frequent monitoring of lithium levels in blood plasma. Nimesulide may increase the strength of the side effects of methotrexate, so it can be used 24 hours. or after 24 hours. after methotrexate administration. Nimesulide may increase the effects of cyclosporin kidneys.
Patients with impaired renal function, renal function impairment Some minor or moderate (creatinine clearance 30-80 ml / min.), A dose reduction is required. When severe renal impairment (creatinine clearance <30 ml / min). Nimesil prohibited.
Acute non-steroidal anti-inflammatory drugs overdose usually resulting symptoms include lethargy, drowsiness, nausea, vomiting, pain in the epigastric region, which, using supportive measures disappears. May include bleeding from the gastrointestinal tract. Although rare, but it can increase blood pressure, acute renal failure, respiratory depression, coma. The use of nonsteroidal anti-inflammatory therapeutic doses may be anaphylaxis-like reactions; they can be and medicine overdose
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